We discuss exotic nuclei including charm and bottom flavors, and propose stable
exotic nuclei bound with $\bar{D}$ and $B$ mesons with respecting heavy quark
symmetry. We discuss that an approximate degeneracy of $\bar{D}$($B$) and
$\bar{D}^{*}$($B^{*}$) mesons plays an important role, and investigate the
stability of $\bar{D}N$ and $BN$ bound states. We find the $\bar{D}N$ and $BN$
bound states in the $J^{P}=1/2^{-}$ with I=0 channel. We discuss also possible
existence of exotic nuclei $\bar{D}NN$ and $BNN$. We propose experiments to
observe these exotic nuclei which are accessible in accelerator facilities such
as  J-PARC and GSI.